Pyrene–nucleobase conjugates: synthesis, oligonucleotide binding and confocal bioimaging studies

Pyrene–nucleobase conjugates: synthesis, oligonucleotide binding and confocal bioimaging studies

Fluorescent pyrene–linker–nucleobase (nucleobase = thymine, adenine) conjugates with carbonyl and hydroxy functionalities in the linker were synthesized and characterized. X-ray single-crystal structure analysis performed for the pyrene–C(O)CH2CH2–thymine (2) conjugate reveals dimers of molecules 2...

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Bibliographic Details
Main Authors: Artur Jabłoński, Yannic Fritz, Hans-Achim Wagenknecht, Rafał Czerwieniec, Tytus Bernaś, Damian Trzybiński, Krzysztof Woźniak, Konrad Kowalski
Format: Article
Language:English
Published: Beilstein-Institut 2017-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
confocal microscopy
luminescence
nucleobases
oligonucleotide binding
pyrene
X-ray
Online Access:https://doi.org/10.3762/bjoc.13.249

Internet

https://doi.org/10.3762/bjoc.13.249

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