Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First?

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder. Its characteristic neuropathological features encompass the loss of dopaminergic neurons of the nigrostriatal system and the presence of Lewy bodies and Lewy neurites. These are intraneuronal and intraneuritic proteinac...

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Bibliographic Details
Main Authors: Michela Zaltieri, Francesca Longhena, Marina Pizzi, Cristina Missale, PierFranco Spano, Arianna Bellucci
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2015/108029