Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline

Infection with the filarial nematode Wuchereria bancrofti can lead to lymphedema, hydrocele, and elephantiasis. Since adult worms cause pathology in lymphatic filariasis (LF), it is imperative to discover macrofilaricidal drugs for the treatment of the infection. Endosymbiotic Wolbachia in filariae...

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Bibliographic Details
Main Authors: Alexander Yaw Debrah, Sabine Mand, Yeboah Marfo-Debrekyei, Linda Batsa, Anna Albers, Sabine Specht, Ute Klarmann, Kenneth Pfarr, Ohene Adjei, Achim Hoerauf
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2011/201617