Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays

Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays

Although coffee components have gained interest for use as pharmaceuticals, little is known about their safety pharmacological effects. Hence, we aimed to evaluate the safety pharmacological effects of a chlorogenic acid (CGA)-related compound contained in coffee, 5-<i>O</i>-caffeoylquin...

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Bibliographic Details
Main Authors: Yuto Amano, Hiroshi Honda, Yuko Nukada, Naohiro Ikeda, Masayuki Yamane, Koji Nakano, Akiyo Kameyama, Osamu Morita
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceuticals
Subjects:
safety pharmacology
chlorogenic acid
caffeoylquinic acid
coffee
adverse effects
bioactive compounds
cardiovascular system
central nervous system
gastrointestinal system
Online Access:https://www.mdpi.com/1424-8247/12/3/110

Internet

https://www.mdpi.com/1424-8247/12/3/110

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