H2A ubiquitination is essential for Polycomb Repressive Complex 1-mediated gene regulation in Marchantia polymorpha

H2A ubiquitination is essential for Polycomb Repressive Complex 1-mediated gene regulation in Marchantia polymorpha

Abstract Background Polycomb repressive complex 1 (PRC1) and PRC2 are chromatin regulators maintaining transcriptional repression. The deposition of H3 lysine 27 tri-methylation (H3K27me3) by PRC2 is known to be required for transcriptional repression, whereas the contribution of H2A ubiquitination...

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Bibliographic Details
Main Authors: Shujing Liu, Minerva S. Trejo-Arellano, Yichun Qiu, D. Magnus Eklund, Claudia Köhler, Lars Hennig
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genome Biology
Subjects:
H2Aub
H3K27me3
Gene regulation
Polycomb
PRC1
Marchantia polymorpha
Online Access:https://doi.org/10.1186/s13059-021-02476-y

Internet

https://doi.org/10.1186/s13059-021-02476-y

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