Engineering Strategies to Enhance TCR-Based Adoptive T Cell Therapy

T cell receptor (TCR)-based adoptive T cell therapies (ACT) hold great promise for the treatment of cancer, as TCRs can cover a broad range of target antigens. Here we summarize basic, translational and clinical results that provide insight into the challenges and opportunities of TCR-based ACT. We...

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Bibliographic Details
Main Authors: Jan A. Rath, Caroline Arber
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/6/1485