Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

Abstract Background Recent findings describe microglia as modulators of neurogenesis in the subventricular zone (SVZ). SVZ microglia in the adult rat are thought to adopt a neurotrophic phenotype after ischemic stroke. Early postnatal microglia are endogenously activated and may therefore exhibit an...

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Bibliographic Details
Main Authors: Urs Fisch, Catherine Brégère, Florian Geier, Laurie Chicha, Raphael Guzman
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Subventricular zone
Hypoxia-ischemia
Development
Neurogenesis
Rat
Online Access:https://doi.org/10.1186/s12974-020-1706-y

Internet

https://doi.org/10.1186/s12974-020-1706-y

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