Profile of entrectinib in the treatment of ROS1-positive non-small cell lung cancer: Evidence to date

ROS proto-oncogene 1 (ROS1) encodes a type I integral membrane protein with tyrosine kinase activity and whose activating alterations are involved in the aggressiveness of several tumor types. Fusions involving ROS1 gene are present in 1–2% of lung adenocarcinomas and other solid tumors. Entrectinib...

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Bibliographic Details
Main Authors: Jhajaira M. Araujo, Andrea C. Gomez, Joseph A. Pinto, Christian Rolfo, Luis E. Raez
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387620301771