Zincophorin – biosynthesis in Streptomyces griseus and antibiotic properties

Zincophorin is a polyketide antibiotic that possesses potent activity against Gram-positive bacteria, including human pathogens. While a number of total syntheses of this highly functionalized natural product were reported since its initial discovery, the genetic basis for the biosynthesis of zincop...

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Bibliographic Details
Main Authors: Walther, Elisabeth, Boldt, Sabrina, Kage, Hirokazu, Lauterbach, Tom, Martin, Karin, Roth, Martin, Hertweck, Christian, Sauerbrei, Andreas, Schmidtke, Michaela, Nett, Markus
Format: Article
Language:English
Published: German Medical Science GMS Publishing House 2016-11-01
Series:GMS Infectious Diseases
Subjects:
Online Access:http://www.egms.de/static/en/journals/id/2016-4/id000026.shtml