MicroRNA-450a-3p represses cell proliferation and regulates embryo development by regulating Bub1 expression in mouse.

MicroRNA-450a-3p represses cell proliferation and regulates embryo development by regulating Bub1 expression in mouse.

Bub1 is a critical component of the spindle assembly checkpoint (SAC) and closely linked to cell proliferation and differentiation. We previously found that spontaneous abortion embryos contained a low level of Bub1 protein but normal mRNA level, while the knockdown of Bub1 leads to abnormal numeric...

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Bibliographic Details
Main Authors: Min Luo, Yaguang Weng, Jian Tang, Min Hu, Qiang Liu, Fengbing Jiang, Dandan Yang, Chen Liu, Xiaoqin Zhan, Peipei Song, Huili Bai, Baolin Li, Qiong Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3478270?pdf=render

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http://europepmc.org/articles/PMC3478270?pdf=render

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