Syndromic Craniosynostosis Can Define New Candidate Genes for Suture Development or Result from the Non-specifc Effects of Pleiotropic Genes: Rasopathies and Chromatinopathies as Examples

Syndromic Craniosynostosis Can Define New Candidate Genes for Suture Development or Result from the Non-specifc Effects of Pleiotropic Genes: Rasopathies and Chromatinopathies as Examples

Craniosynostosis is a heterogeneous condition caused by the premature fusion of cranial sutures, occurring mostly as an isolated anomaly. Pathogenesis of non-syndromic forms of craniosynostosis is largely unknown. In about 15–30% of cases craniosynostosis occurs in association with other physical an...

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Bibliographic Details
Main Authors: Marcella Zollino, Serena Lattante, Daniela Orteschi, Silvia Frangella, Paolo N. Doronzio, Ilaria Contaldo, Eugenio Mercuri, Giuseppe Marangi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Neuroscience
Subjects:
craniosynostosis
chromatinopathies
neurocristopathies
RASopathies
Kabuki syndrome
Koolen-De-Vries syndrome
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00587/full

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http://journal.frontiersin.org/article/10.3389/fnins.2017.00587/full

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