MicroRNA-218 Negatively Regulates Osteoclastogenic Differentiation by Repressing the Nuclear Factor-κB Signaling Pathway and Targeting Tumor Necrosis Factor Receptor 1

MicroRNA-218 Negatively Regulates Osteoclastogenic Differentiation by Repressing the Nuclear Factor-κB Signaling Pathway and Targeting Tumor Necrosis Factor Receptor 1

Background/Aims: Postmenopausal osteoporosis is a common disease associated with estrogen deficiency leading to bone loss and bone tissue changes. The resultant bone fragility and increased risk of fracture has serious adverse effects on health and quality of life of the elderly, making it an import...

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Bibliographic Details
Main Authors: Weiwei Wang, Lei Yang, Dan Zhang, Chao Gao, Jie Wu, Yunxia Zhu, Hogxiu Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Postmenopausal osteoporosis
MiR-218
TNFR1
NF-κB
Osteoclast differentiation
Online Access:https://www.karger.com/Article/FullText/491740

Internet

https://www.karger.com/Article/FullText/491740

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