Evaluation of a phenotype imputation approach using GAW20 simulated data

Abstract Statistical power, which is the probability of correctly rejecting a false null hypothesis, is a limitation of genome-wide association studies (GWAS). Sample size is a major component of statistical power that can be easily affected by missingness in phenotypic data and restrain the ability...

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Bibliographic Details
Main Authors: Yuning Chen, Gina M. Peloso, Josée Dupuis
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0134-9