The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.

The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.

Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus (SLE) and can mediate disease pathogenesis by the formation of immune complexes. Since blocking immune complex formation can attenuate disease manifestations, the effects of nucleic acid binding polymers (NABPs...

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Bibliographic Details
Main Authors: Nancy A Stearns, Jaewoo Lee, Kam W Leong, Bruce A Sullenger, David S Pisetsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3394750?pdf=render

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http://europepmc.org/articles/PMC3394750?pdf=render

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