The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica.

Recurrent myelitis is one of the predominant characteristics in patients with neuromyelitis optica (NMO). While paresis, visual loss, sensory deficits, and bladder dysfunction are well known symptoms in NMO patients, pain has been recognized only recently as another key symptom of the disease. Altho...

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Bibliographic Details
Main Authors: Hannah L Pellkofer, Joachim Havla, Daniela Hauer, Gustav Schelling, Shahnaz C Azad, Tania Kuempfel, Walter Magerl, Volker Huge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3739748?pdf=render