Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease

Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease

BACKGROUND CD64 (FcγR1) is a high-affinity receptor for monomeric IgG1 and IgG3. Circulating neutrophils express very low amounts of CD64 on their surface. OBJECTIVES Our primary aim was to investigate the utility of neutrophil CD64 surface expression as a biomarker of active pulmonary tuberculos...

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Bibliographic Details
Main Authors: Raquel da Silva Corrêa, Luciana Silva Rodrigues, Leticia Hagge Lima Pereira, Otto Castro Nogueira, Janaína Leung, Marcela da S Sousa, Mariana de Andrea Hacker, Helio Ribeiro de Siqueira, Domênico Capone, Rogério Lopes Rufino Alves, Maria Cristina Vidal Pessolani, Veronica Schmitz, Geraldo Moura Batista Pereira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
tuberculosis
latent tuberculosis infection
biomarkers
neutrophils
CD64
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100319&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100319&lng=en&tlng=en

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