Actinomycin V Inhibits Migration and Invasion via Suppressing Snail/Slug-Mediated Epithelial-Mesenchymal Transition Progression in Human Breast Cancer MDA-MB-231 Cells In Vitro

Actinomycin V Inhibits Migration and Invasion via Suppressing Snail/Slug-Mediated Epithelial-Mesenchymal Transition Progression in Human Breast Cancer MDA-MB-231 Cells In Vitro

Actinomycin V, an analog of actinomycin D produced by the marine-derived actinomycete <i>Streptomyces</i> sp., possessing a 4-ketoproline instead of a 4-proline in actinomycin D. In this study, the involvement of snail/slug-mediated epithelial-mesenchymal transition (EMT) in the anti-mig...

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Bibliographic Details
Main Authors: Shiqi Lin, Caiyun Zhang, Fangyuan Liu, Jiahui Ma, Fujuan Jia, Zhuo Han, Weidong Xie, Xia Li
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Marine Drugs
Subjects:
breast cancer
actinomycin
EMT
migration
invasion
Online Access:https://www.mdpi.com/1660-3397/17/5/305

Internet

https://www.mdpi.com/1660-3397/17/5/305

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