MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.

BACKGROUND AIMS: Gastric cancer is the most frequent gastrointestinal tumor in adults and is the most lethal form of human cancer. Despite of the improvements in treatments, the underlying mechanism of gastric carcinogenesis is not well known. To define novel modulators that regulate susceptibility...

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Bibliographic Details
Main Authors: Huizi Lei, Dongling Zou, Zheng Li, Min Luo, Lei Dong, Bin Wang, Haixin Yin, Yanni Ma, Changzheng Liu, Fang Wang, Junwu Zhang, Jia Yu, Yu Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634036?pdf=render