Severe chronic kidney disease environment reduced calcium-sensing receptor expression in parathyroid glands of adenine-induced rats even without high phosphorus diet

Severe chronic kidney disease environment reduced calcium-sensing receptor expression in parathyroid glands of adenine-induced rats even without high phosphorus diet

Abstract Background Chronic kidney disease (CKD) disrupts mineral homeostasis and its main underlying cause is secondary hyperparathyroidism (SHPT). We previously reported that calcium-sensing receptor (CaSR) mRNA and protein expression in parathyroid glands (PTGs) significantly decreased in a CKD r...

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Bibliographic Details
Main Authors: Taketo Uchiyama, Ichiro Ohkido, Akio Nakashima, Yatsumu Saito, Masataka Okabe, Takashi Yokoo
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Nephrology
Subjects:
Calcium-sensing receptor
Vitamin D receptor
Glial cells missing 2
CKD-MBD
Secondary hyperparathyroidism
Online Access:http://link.springer.com/article/10.1186/s12882-020-01880-z

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http://link.springer.com/article/10.1186/s12882-020-01880-z

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