XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans.

XRN2 is a conserved 5'→3' exoribonuclease that complexes with proteins that contain XRN2-binding domains (XTBDs). In Caenorhabditis elegans (C. elegans), the XTBD-protein PAXT-1 stabilizes XRN2 to retain its activity. XRN2 activity is also promoted by 3'(2'),5'-bisphosphate...

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Bibliographic Details
Main Authors: Takashi S Miki, Sarah H Carl, Michael B Stadler, Helge Großhans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5025045?pdf=render