Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon

Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon

BACKGROUND The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised by three variants: VK210, VK247 and P. vivax-like. The most important challenge in the treatment of P. vivax infection is the poss...

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Bibliographic Details
Main Authors: Lilian Rose Pratt-Riccio, Bárbara de Oliveira Baptista, Vanessa Rodrigues Torres, Cesare Bianco-Junior, Daiana de Souza Perce-Da-Silva, Evelyn Kety Pratt Riccio, Josué da Costa Lima-Junior, Paulo Renato Rivas Totino, Gustavo Capatti Cassiano, Luciane Moreno Storti-Melo, Ricardo Luiz Dantas Machado, Joseli de Oliveira-Ferreira, Dalma Maria Banic, Leonardo José de Moura Carvalho, Cláudio Tadeu Daniel-Ribeiro
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
malaria
Plasmodium vivax
circumsporozoite protein
chemoresistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100340&lng=en&tlng=en

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