Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B

<p>Abstract</p> <p>Background</p> <p>Controversy exists regarding the role of PD1 and its ligand PD-L1 in chronic hepatitis B infection. In some studies, persistent HBV infection has been attributed to high levels of PD-1 and PD-L1 expression on HBV-specific T-cells and...

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Bibliographic Details
Main Authors: Wenjin Zhang, Chuanhui Peng, Yunle Wan, Lateef Shaikh, Shusen Zheng
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Gastroenterology
Subjects:
PD1
Online Access:http://www.biomedcentral.com/1471-230X/12/109