Pain modulation by nitric oxide in the spinal cord.

Nitric oxide (NO) is a versatile messenger molecule first associated with endothelial relaxing effects. In the central nervous system (CNS), NO synthesis is primarily triggered by activation of N-methyl-D-aspartate (NMDA) receptors and has a Janus face, with both beneficial and harmful properties, d...

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Bibliographic Details
Main Authors: Marco Aurelio M Freire, Joanilson S Guimarães, Walace Gomes-Leal, Antonio Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.01.024.2009/full