Studies on the virulence and attenuation of Trypanosoma cruzi using immunodeficient animals

Tissue invasion and pathology by Trypanosoma cruzi result from an interaction between parasite virulence and host immunity. Successive in vivo generations of the parasite select populations with increasing ability to invade the host. Conversely, prolonged in vitro selection of the parasite produces...

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Bibliographic Details
Main Authors: Basombrío Miguel Ángel, Segura María Asunción, Gómez Laura, Padilla Marcelo
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2000-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000700029