Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders

Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders

Abstract Neuropsychiatric disorders, such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major depressive disorder (MDD) share common clinical presentations, suggesting etiologic overlap. A substantial proportion o...

Full description

Bibliographic Details
Main Authors:	Xueming Yao, Joseph T. Glessner, Junyi Li, Xiaohui Qi, Xiaoyuan Hou, Chonggui Zhu, Xiaoge Li, Michael E. March, Liu Yang, Frank D. Mentch, Heather S. Hain, Xinyi Meng, Qianghua Xia, Hakon Hakonarson, Jin Li
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-01-01
Series:	Translational Psychiatry
Online Access:	https://doi.org/10.1038/s41398-020-01195-5

Similar Items

Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils
by: Junyi Li, et al.
Published: (2019-03-01)

Target Genes of Autism Risk Loci in Brain Frontal Cortex
by: Yan Sun, et al.
Published: (2019-08-01)

Genome-wide association study of maternal and inherited loci for conotruncal heart defects.
by: A J Agopian, et al.
Published: (2014-01-01)

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature
by: Frackelton Edward C, et al.
Published: (2010-06-01)

HIF-1α Pulmonary Phenotype Wide Association Study Unveils a Link to Inflammatory Airway Conditions
by: Jelte Kelchtermans, et al.
Published: (2021-09-01)

Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations
by: Rana Dajani, et al.
Published: (2017-08-01)

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
by: Jonathan P Bradfield, et al.
Published: (2011-09-01)

The Multi-Omics Architecture of Juvenile Idiopathic Arthritis
by: Xiaoyuan Hou, et al.
Published: (2020-10-01)

A genome-wide association study on obesity and obesity-related traits.
by: Kai Wang, et al.
Published: (2011-04-01)

Genome-wide association study of serum minerals levels in children of different ethnic background.
by: Xiao Chang, et al.
Published: (2015-01-01)

Phenotype restricted genome-wide association study using a gene-centric approach identifies three low-risk neuroblastoma susceptibility Loci.
by: Le B Nguyen, et al.
Published: (2011-03-01)

Discovery of Novel Host Molecular Factors Underlying HBV/HCV Infection
by: Xubo Huang, et al.
Published: (2021-08-01)

Correction: A Genome-Wide Association Study on Obesity and Obesity-Related Traits
by: Kai Wang, et al.
Published: (2012-01-01)

Correction: A Genome-Wide Association Study on Obesity and Obesity-Related Traits.
by: Kai Wang, et al.
Published: (2012-01-01)

Genome-wide association study reveals novel loci associated with feeding behavior in Pekin ducks
by: Guang-Sheng Li, et al.
Published: (2021-05-01)

Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits
by: Bingxin Zhao, et al.
Published: (2021-05-01)

Genetic architecture study of rheumatoid arthritis and juvenile idiopathic arthritis
by: Jun Jia, et al.
Published: (2020-01-01)

Rare variants create synthetic genome-wide associations.
by: Samuel P Dickson, et al.
Published: (2010-01-01)

Identification of Major Quantitative Trait Loci for Seed Oil Content in Soybeans by Combining Linkage and Genome-Wide Association Mapping
by: Yongce Cao, et al.
Published: (2017-07-01)

Genome-Wide Association Study Identifies Loci Associated with Sensitive Skin
by: Miranda A. Farage, et al.
Published: (2020-06-01)

Association of Rare Recurrent Copy Number Variants With Congenital Heart Defects Based on Next-Generation Sequencing Data From Family Trios
by: Yichuan Liu, et al.
Published: (2019-09-01)

Genome wide association study identifies four loci for early onset schizophrenia
by: Suqin Guo, et al.
Published: (2021-04-01)

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression
by: Zheng Zeng, et al.
Published: (2021-03-01)

Genome-wide association study identifies four loci associated with eruption of permanent teeth.
by: Frank Geller, et al.
Published: (2011-09-01)

Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
by: Hui-Qi Qu, et al.
Published: (2021-07-01)

Epigenetic editing to validate findings from methylome-wide association studies of neuropsychiatric disorders
by: Chan, Robin F.
Published: (2017)

Computational analyses of obesity associated loci generated by genome-wide association studies.
by: Mengrong Cheng, et al.
Published: (2018-01-01)

Genome-wide association study identifies genetic loci associated with iron deficiency.
by: Christine E McLaren, et al.
Published: (2011-03-01)

Genetic variation in genes encoding airway epithelial potassium channels is associated with chronic rhinosinusitis in a pediatric population.
by: Michael T Purkey, et al.
Published: (2014-01-01)

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.
by: Zhi Wei, et al.
Published: (2009-10-01)

Genome-wide association study link novel loci to endometriosis.
by: Hans M Albertsen, et al.
Published: (2013-01-01)

Genome-wide identification of loci associated with growth in rainbow trout
by: Ali Ali, et al.
Published: (2020-03-01)

Genome-wide association analysis identifies loci governing mercury accumulation in maize
by: Zhan Zhao, et al.
Published: (2017-03-01)

Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci
by: Andrulis, I., et al.
Published: (2022)

Genome-Wide Association Analysis Reveals Loci and Candidate Genes Involved in Fiber Quality Traits Under Multiple Field Environments in Cotton (Gossypium hirsutum)
by: Xiaohui Song, et al.
Published: (2021-08-01)

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
by: Egil Ferkingstad, et al.
Published: (2018-11-01)

Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle
by: Qiuming Chen, et al.
Published: (2020-03-01)

Genome-Wide Association Study Identifies Candidate Loci Associated with Platelet Count in Koreans
by: Ji Hee Oh, et al.
Published: (2014-12-01)

Genome-Wide Association Studies Identifying Multiple Loci Associated With Alfalfa Forage Quality
by: Sen Lin, et al.
Published: (2021-06-01)

Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia
by: Yong-Biao Zhang, et al.
Published: (2016-02-01)