A multicenter case–control study of the effect of e-nos VNTR polymorphism on upper gastrointestinal hemorrhage in NSAID users

Abstract Bleeding in non-steroidal anti-inflammatory drug (NSAID) users limited their prescription. This first multicenter full case–control study (325 cases and 744 controls), explored the association of e-NOS intron 4 variable number tandem repeat (VNTR) polymorphism with upper gastrointestinal he...

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Bibliographic Details
Main Authors: Narmeen Mallah, Maruxa Zapata-Cachafeiro, Carmelo Aguirre, Eguzkiñe Ibarra-García, Itziar Palacios–Zabalza, Fernando Macías García, Julio iglesias García, María Piñeiro-Lamas, Luisa Ibáñez, Xavier Vidal, Lourdes Vendrell, Luis Martin-Arias, María Sáinz Gil, Verónica Velasco-González, Ángel Salgado-Barreira, Adolfo Figueiras
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99402-w