A novel method for identification and quantification of consistently differentially methylated regions.

Advances in biotechnology have resulted in large-scale studies of DNA methylation. A differentially methylated region (DMR) is a genomic region with multiple adjacent CpG sites that exhibit different methylation statuses among multiple samples. Many so-called "supervised" methods have been...

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Bibliographic Details
Main Authors: Ching-Lin Hsiao, Ai-Ru Hsieh, Ie-Bin Lian, Ying-Chao Lin, Hui-Min Wang, Cathy S J Fann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018258?pdf=render