ExoU contributes to late killing of Pseudomonas aeruginosa - infected endothelial cells ExoU contribui para a morte tardia de células endoteliais infectadas por Pseudomonas aeruginosa

ExoU contributes to late killing of Pseudomonas aeruginosa - infected endothelial cells ExoU contribui para a morte tardia de células endoteliais infectadas por Pseudomonas aeruginosa

To ascertain the role of ExoU in late P. aeruginosa cytotoxicity, endothelial cells (EC) were exposed to wild type PA103, PA103deltaexoU and PA103::exsA for 1h and to gentamicin in culture medium. After 24h, the viability of PA103-infected cells (33.7 ± 14.3%) was significantly lower than the viabil...

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Bibliographic Details
Main Authors: Alessandra Mattos Saliba, Rebeca Nishi, Maria Cristina Assis, Maria Cristina Plotkowski
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2003-11-01
Series:Brazilian Journal of Microbiology
Subjects:
Sistema de secreção do tipo III
ExoU
células endoteliais
citotoxicidade bacteriana
Type III secretion system
endothelial cells
bacterial cytotoxicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000500008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000500008

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