Computer-assisted image analysis of the tumor microenvironment on an oral tongue squamous cell carcinoma tissue microarray

Oral tongue squamous cell carcinoma (OTSCC) displays variable levels of immune cells within the tumor microenvironment. The quantity and localization of tumor infiltrating lymphocytes (TILs), specific functional TIL subsets (e.g., CD8+), and biomarker-expressing cells (e.g., PD-L1+) may have prognos...

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Bibliographic Details
Main Authors: Sangjune Laurence Lee, Michael Cabanero, Martin Hyrcza, Marcus Butler, Fei-Fei Liu, Aaron Hansen, Shao Hui Huang, Ming-Sound Tsao, Yuyao Song, Lin Lu, Wei Xu, Douglas B. Chepeha, David P. Goldstein, Ilan Weinreb, Scott V. Bratman
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630819300175