Hepatitis C virus non-structural protein 3 interacts with cytosolic 5'(3')-deoxyribonucleotidase and partially inhibits its activity.

Infection with hepatitis C virus (HCV) is etiologically involved in liver cirrhosis, hepatocellular carcinoma and B-cell lymphomas. It has been demonstrated previously that HCV non-structural protein 3 (NS3) is involved in cell transformation. In this study, a yeast two-hybrid screening experiment w...

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Bibliographic Details
Main Authors: Chiu-Ping Fang, Zhi-Cheng Li, Chee-Hing Yang, Ju-Chien Cheng, Yung-Ju Yeh, Tsai-Hsia Sun, Hui-Chun Li, Yue-Li Juang, Shih-Yen Lo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706368?pdf=render