Case–control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood

Abstract CD4 T cell phenotyping-based blood assays have the potential to meet WHO target product profiles (TPP) of non-sputum-biomarker-based tests to diagnose tuberculosis (TB). Yet, substantial refinements are required to allow their implementation in clinical settings. This study assessed the rea...

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Bibliographic Details
Main Authors: Hellen Hiza, Jerry Hella, Ainhoa Arbués, Beatrice Magani, Mohamed Sasamalo, Sebastien Gagneux, Klaus Reither, Damien Portevin
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92596-z