Cell Surface Binding and Lipid Interactions behind Chemotherapy-Drug-Induced Ion Pore Formation in Membranes

Chemotherapy drugs (CDs) disrupt the lipid membrane’s insulation properties by inducing stable ion pores across bilayer membranes. The underlying molecular mechanisms behind pore formation have been revealed in this study using several methods that confirm molecular interactions and detect associate...

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Bibliographic Details
Main Authors: Md. Ashrafuzzaman, Zahid Khan, Ashwaq Alqarni, Mohammad Alanazi, Mohammad Shahabul Alam
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/7/501