Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer

Boosting natural immunity against malignant cells has had a major breakthrough in clinical cancer therapy. This is mainly due to the successful development of immune checkpoint blocking antibodies, which release a break on cytolytic anti-tumor-directed T-lymphocytes. However, immune checkpoint block...

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Bibliographic Details
Main Authors: Maria Georganaki, Luuk van Hooren, Anna Dimberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03081/full