Distinct molecular features of different macroscopic subtypes of colorectal neoplasms.

Distinct molecular features of different macroscopic subtypes of colorectal neoplasms.

Colorectal adenoma develops into cancer with the accumulation of genetic and epigenetic changes. We studied the underlying molecular and clinicopathological features to better understand the heterogeneity of colorectal neoplasms (CRNs).We evaluated both genetic (mutations of KRAS, BRAF, TP53, and PI...

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Main Authors: Kenichi Konda, Kazuo Konishi, Toshiko Yamochi, Yoichi M Ito, Hisako Nozawa, Masayuki Tojo, Kensuke Shinmura, Mari Kogo, Atsushi Katagiri, Yutaro Kubota, Takashi Muramoto, Yuichiro Yano, Yoshiya Kobayashi, Toshihiro Kihara, Teppei Tagawa, Reiko Makino, Masafumi Takimoto, Michio Imawari, Hitoshi Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4122357?pdf=render

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http://europepmc.org/articles/PMC4122357?pdf=render

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