Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.

Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.

Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose. Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function. We hypothesized that FLG mutation carriers would be more susceptible to human pa...

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Bibliographic Details
Main Authors: Tea Skaaby, Lise Lotte N Husemoen, Torben Jørgensen, Jeanne D Johansen, Torkil Menné, Pal B Szecsi, Steen Stender, Peter Bager, Jacob P Thyssen, Allan Linneberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4048243?pdf=render

Internet

http://europepmc.org/articles/PMC4048243?pdf=render

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