A Computational Model of the Cholinergic Modulation of CA1 Pyramidal Cell Activity

Dysfunction in cholinergic modulation has been linked to a variety of cognitive disorders including Alzheimer's disease. The important role of this neurotransmitter has been explored in a variety of experiments, yet many questions remain unanswered about the contribution of cholinergic modulati...

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Bibliographic Details
Main Authors: Adam Mergenthal, Jean-Marie C. Bouteiller, Gene J. Yu, Theodore W. Berger
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Computational Neuroscience
Subjects:
CA1
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2020.00075/full