Involvement of atypical protein kinase C in the regulation of cardiac glucose and long-chain fatty acid uptake

Involvement of atypical protein kinase C in the regulation of cardiac glucose and long-chain fatty acid uptake

Aim: The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/ long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of atypical PKCs (PKC-ζ and PKC-λ) in regulating card...

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Bibliographic Details
Main Authors: Daphna D.J. Habets, Joost J.F.P. Luiken, Margriet eOuwens, Will A. Coumans, Monique eVergouwe, Stine J. Maarbjerg, Michael eLeitges, Arend eBonen, Erik A. Richter, Jan eGlatz
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Physiology
Subjects:
Insulin
cardiomyocytes
AMPK
CD36
atypical PKC
fatty acid uptake
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00361/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00361/full

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