Pathogenesis and potential therapy of autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by progressive growth of the cyst and an increase in the total volume of the kidneys which leads to kidney failure. The main causes of ADPKD are mutations in the genes PKD1 and PKD2 which encode the formation...

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Bibliographic Details
Main Author: O.O. Melnyk
Format: Article
Language:English
Published: Publishing House Zaslavsky 2017-10-01
Series:Počki
Subjects:
Online Access:http://kidneys.zaslavsky.com.ua/article/view/114054