An improved classification of G-protein-coupled receptors using sequence-derived features

<p>Abstract</p> <p>Background</p> <p>G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures of GPCRs are largely unavailable; however, a large number of GP...

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Bibliographic Details
Main Authors: Peng Zhen-Ling, Yang Jian-Yi, Chen Xin
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/420