Oxidative stress mediates depot-specific functional differences of human adipose-derived stem cells

Oxidative stress mediates depot-specific functional differences of human adipose-derived stem cells

Abstract Background Visceral (VS) fat depot is known to have defective adipogenic functions compared to subcutaneous (SC) fat, but its mechanism of origin is unclear. Objective We tested our hypothesis that the degree of oxidative stress in adipose-derived stem cells (ASCs) from these depots may acc...

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Bibliographic Details
Main Authors: Sandhya Sriram, Chengxiang Yuan, Smarajit Chakraborty, Winson Tay, Min Park, Asim Shabbir, Sue-Anne Toh, Weiping Han, Shigeki Sugii
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Stem Cell Research & Therapy
Subjects:
Subcutaneous fat
Intra-abdominal fat
Mesenchymal stromal cells
Oxidative stress
Reactive oxygen species
Ascorbic acid
Online Access:http://link.springer.com/article/10.1186/s13287-019-1240-y

Internet

http://link.springer.com/article/10.1186/s13287-019-1240-y

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