Multicellular Models Bridging Intracellular Signaling and Gene Transcription to Population Dynamics

Multicellular Models Bridging Intracellular Signaling and Gene Transcription to Population Dynamics

Cell signaling and gene transcription occur at faster time scales compared to cellular death, division, and evolution. Bridging these multiscale events in a model is computationally challenging. We introduce a framework for the systematic development of multiscale cell population models. Using messa...

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Bibliographic Details
Main Authors: Mohammad Aminul Islam, Satyaki Roy, Sajal K. Das, Dipak Barua
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Processes
Subjects:
multiscale modeling
message passing interface
Gillespie method
cell population dynamics
quorum sensing
Online Access:https://www.mdpi.com/2227-9717/6/11/217

Internet

https://www.mdpi.com/2227-9717/6/11/217

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