Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease

Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease

Abstract Background and aim Toxic oligomeric α-synuclein (αS; O-αS) has been suggested to play a central role in the pathogenesis of Lewy body diseases such as Parkinson’s disease (PD). Cerebrospinal fluid (CSF) levels of αS, O-αS, total and phosphorylated tau, and amyloid β 1–42 (Aβ1–42) are though...

Full description

Bibliographic Details
Main Authors: Hidetomo Murakami, Takahiko Tokuda, Omar M. A. El-Agnaf, Takuma Ohmichi, Ayako Miki, Hideaki Ohashi, Yoshiyuki Owan, Yu Saito, Satoshi Yano, Tamao Tsukie, Takeshi Ikeuchi, Kenjiro Ono
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Neurology
Subjects:
Parkinson’s disease
α-Synuclein
Oligomer
Amyloid β-protein (1–42)
Tau protein
Clinical symptom
Online Access:http://link.springer.com/article/10.1186/s12883-019-1346-y

Internet

http://link.springer.com/article/10.1186/s12883-019-1346-y

Similar Items