Metformin protects from oxaliplatin induced peripheral neuropathy in rats

Oxaliplatin is a commonly used drug to treat cancer, extending the rate of disease-free survival by 20% in colorectal cancer. However, oxaliplatin induces a disabling form of neuropathy resulting in more than 60% of patients having to reduce or discontinue oxaliplatin, negatively impacting their cha...

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Bibliographic Details
Main Authors: N.W. Martinez, A. Sánchez, P. Diaz, R. Broekhuizen, J. Godoy, S. Mondaca, A. Catenaccio, P. Macanas, B. Nervi, M. Calvo, F.A. Court
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Neurobiology of Pain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X20300064