Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's Disease, is a late-onset X-linked progressive neuromuscular disease, which predominantly affects males. The pathological hallmarks of the disease are selective loss of spinal and bulbar motor neurons, accompanied by weakness, at...

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Bibliographic Details
Main Authors: Anna L. Gray, Leonette Annan, James R. T. Dick, Albert R. La Spada, Michael G. Hanna, Linda Greensmith, Bilal Malik
Format: Article
Language:English
Published: The Company of Biologists 2020-05-01
Series:Disease Models & Mechanisms
Subjects:
sbma
androgen receptor
muscle
myopathy
neuromuscular disease
spinal and bulbar muscular atrophy
Online Access:http://dmm.biologists.org/content/13/5/dmm042424

Internet

http://dmm.biologists.org/content/13/5/dmm042424

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