CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways
Objective: In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage. Here we analyzed CCL2 downstream signaling mediators that lead to gene expression of ca...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Osteoarthritis and Cartilage Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665913120301369 |