Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells

Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells

Although mesenchymal stem cells (MSCs) play pivotal supportive roles in hematopoiesis, how they interact with hematopoietic stem cells (HSCs) is not well understood. We investigated the interaction between HSCs and surrogate MSCs (C3H10T1/2 stromal cells), focusing on the molecular events induced b...

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Bibliographic Details
Main Authors: Kikuchi Y, Kume A, Urabe M, Mizukami H, Suzuki T, Ozaki K, Nagai T, Ozawa K
Format: Article
Language:English
Published: GN Corporation Limited 2011-01-01
Series:Journal of Stem Cells and Regenerative Medicine
Subjects:
mesenchymal stromal (stem) cell
hematopoietic stem cell
cell contact
Notch signaling
Online Access:http://www.pubstemcell.com/monthly/007020300010.htm

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http://www.pubstemcell.com/monthly/007020300010.htm

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