Genomic and Epigenetic Advances in Focal Cortical Dysplasia Types I and II: A Scoping Review

Genomic and Epigenetic Advances in Focal Cortical Dysplasia Types I and II: A Scoping Review

Introduction: Focal cortical dysplasias (FCDs) are a group of malformations of cortical development that constitute a common cause of drug-resistant epilepsy, often subjected to neurosurgery, with a suboptimal long-term outcome. The past few years have witnessed a dramatic leap in our understanding...

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Bibliographic Details
Main Authors: Joana Jesus-Ribeiro, Luís Miguel Pires, João Daniel Melo, Ilda Patrícia Ribeiro, Olinda Rebelo, Francisco Sales, António Freire, Joana Barbosa Melo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neuroscience
Subjects:
drug-resistant epilepsy
focal cortical dysplasia
genomics
mTOR pathway
epigenetics
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.580357/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.580357/full

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