High affinity human antibody fragments to dengue virus non-structural protein 3.

BACKGROUND: The enzyme activities catalysed by flavivirus non-structural protein 3 (NS3) are essential for virus replication. They are distributed between the N-terminal protease domain in the first one-third and the C-terminal ATPase/helicase and nucleoside 5' triphosphatase domain which forms...

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Bibliographic Details
Main Authors: Nicole J Moreland, Moon Y F Tay, Elfin Lim, Prasad N Paradkar, Danny N P Doan, Yin Hoe Yau, Susana Geifman Shochat, Subhash G Vasudevan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2976680?pdf=render