Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways

Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways

Neocryptotanshinone (NCTS) is a natural product isolated from traditional Chinese herb Salvia miltiorrhiza Bunge. In this study, we investigated its anti-inflammatory effects in lipopolysaccharide (LPS)-stimulated mouse macrophage (RAW264.7) cells. MTT results showed that NCTS partly reversed LPS-in...

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Bibliographic Details
Main Authors: Chuanhong Wu, Wenwen Zhao, Xuenong Zhang, Xiuping Chen
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Neocryptotanshinone
Inflammation
NF-κB
Inducible nitric oxide synthase
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383515000258

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http://www.sciencedirect.com/science/article/pii/S2211383515000258

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