Zebrafish as a potential model organism for drug test against hepatitis C virus.

Screening and evaluating anti- hepatitis C virus (HCV) drugs in vivo is difficult worldwide, mainly because of the lack of suitable small animal models. We investigate whether zebrafish could be a model organism for HCV replication. To achieve NS5B-dependent replication an HCV sub-replicon was desig...

Full description

Bibliographic Details
Main Authors: Cun-Bao Ding, Jing-Pu Zhang, Ye Zhao, Zong-Gen Peng, Dan-Qing Song, Jian-Dong Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3152561?pdf=render